Effectiveness of ultrasound guided corticoanesthetic injection in carpal tunnel syndrome treatment comparing two different injection sites. Single-blind randomized trial.
Carpal tunnel syndrome (CTS) is the most common nerve entrapment neuropathy. Six placebo-controlled trials with 393 participants proved corticosteroid injection to be effective in symptom relief. However, all injections were palpation-guided. Therefore, the exact injection site was uncertain. Although three studies comparing palpation and ultrasound (US) guided CTS injection showed US superiority, the optimal injection site for the injectate delivery remains unclear. Some authors believe in thinning of the flexor tenosynovium as the mechanism of the median nerve decompression, and therefore recommend injection between the tendons, away from the nerve. Other authors stress the importance of hydrodissection and direct contact of the injectate with the nerve and suggest injection targeting the median nerve. According to our best knowledge, no study comparing different injection sites for a corticosteroid delivery in CTS has been published in English written literature. The objective of this study was to determine the optimal target site for the corticosteroid delivery in CTS injection.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
40
Different Injection Sites (between the flexot tendons or around the median nerve with hydrodissection)
Kamal Mezian
Litoměřice, Czech Republic, Czechia
RECRUITINGKamal Mezian
Litoměřice, Czechia
RECRUITINGVisual analogue scale
pain severity scale
Time frame: up to 1 year
Michigan Hand Outcomes Measure
Hand function status
Time frame: up to 1 year
Boston carpal tunnel questionnaire
Hand function status
Time frame: up to 1 year
Procedural CAS
discomfort during the internetion
Time frame: up to 1 year
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