Visual Perception in Preterm Infants

University Hospital, Strasbourg, France150 enrolled

Overview

We aim to increase our knowledge of the impact of preterm birth on the maturation of the visual and auditory systems and on the development of multisensory perception Specifically, we aim to evaluate the preterm infants' capabilities of detection and discrimination of different visual and auditory stimuli according to gestational age, post menstrual age and the duration of the postnatal life. A secondary aim is to compare this competencies in preterm and full term control art term equivalent age. The final aim is to optimize the hospital environment in order to make it correspond to the expectations and sensory abilities of very preterm infants. Our hypothesis is that preterm birth exposes the infants to numerous atypical stimuli which could accelerate the processes of sensory maturation

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

150

Conditions

Pediatrics

Interventions

Eligibility

Sex: ALLMin age: 23 WeeksMax age: 42 Weeks

Medical Language ↔ Plain English

Inclusion Criteria: * Newborn less than 32 weeks PMA hospitalized in the Hospital of Hautepierre, Strasbourg, France) * Consent obtained from both parents * Social insurance coverage Exclusion Criteria: * Any known malformation * Brain lesions discovered on brain ultrasound (Intra-Ventricular hemorrhage grade III or IV periventricular Leukomalacia). * Unstable clinical State * Retinopathy Of Prematurity stage\> 2 or in zone 1 * Family history of abnormal color vision. * Abnormalities in auditory testing * Transfer to another hospital expected before 40 week PMA

Outcomes

Primary Outcomes

visual stimulus detection with luminance

in "green" condition in hospital, luminance ( 100 and 300 lux ) and color (blue- red-yellow- white) variables

Time frame: 3 months

auditory stimulus detection with parents voice

use parents voice, pure sound of 500 Hz

Time frame: 3 months

Secondary Outcomes

behavioral responsiveness to visual stimuli calibrated collected from video recordings

Evaluate the facial expression of the imitation abilities in preterm and term neonates at term. The interpretation of the behavioral responses of newborns to mimic presented by the experimenter will be working independently by two observers with a coding grid

Time frame: 3 months

Visual Perception in Preterm Infants

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes

Central Contacts