Clinical Trail to Evaluate the Efficacy and Safety of Adhesion Barrier Mediclore Versus no Treatment in Patients With Total Thyroidectomy

Inclusion Criteria: * Written informed consent * Male or female at least 20 years of age * Patients without clinically significant lab * Patients scheduled for thyroidectomy Exclusion Criteria: * Another clinical trials within 1 month * History of previous surgery on same position * Anticoagulant, general steroids within a week from surgery * Immunosuppression or autoimmune disease * General or local infection * Serious diseases (heart failure, renal failure, liver failure, uncontrolled hypertentsion, diabetes mellitus, coagulation deficiencies) * Incompatible medications * History of drug or alcohol abuse, mental disorder * Pregnant or lactating women and fertile women who is not using proper contraceptive method * History of esophagus diseases * Keloid symptoms