Effect of Drinking Fermented Milk on Immune Response

Inclusion Criteria: * 18 45 years old * healthy and having normal vital signs * no history of uncontrolled systemic or autoimmune diseases * no signs or symptoms of respiratory infection * normal blood chemistry including complete blood count (CBC), liver and kidney function, lipid profile and fasting blood sugar * no history of influenza vaccine during the past 6 months * able to continuously take the intervention daily for 6 weeks * able to refrain from other probiotic products such as drinking fermented milk or yoghurt since the beginning till the end of data collection * accepted to receive influenza vaccine shot * able to refrain from receiving other vaccine during the trial * able to refrain from traveling to endemic area of influenza * able to communicate in Thai and sign their written inform consent Exclusion Criteria: * under pregnancy or expected to be pregnant * lactose or milk protein intolerances * daily intake of probiotic product for one month prior to recruitment * chronic alcoholism * GI disturbance e.g. stomachache, frequent diarrhea or constipation * history of GI surgery * ongoing treatment with antibiotic or other immune affecting drugs e.g. glucocorticoids, chemotherapy, antibodies, ciclosporin, hormone and opioids