Infective Endocarditis in the Elderly

Central Hospital, Nancy, France120 enrolled

Overview

ELDERL-IE is a multicenter national prospective observational study. The main objective is to describe geriatric characteristics (comorbidities, cognitive status, autonomy, nutritional status, balance and walking) in patients aged 75 years or older with infective endocarditis (IE). The secondary objectives are to assess the impact of geriatric features on the medico - surgical care and on morbidity and mortality at 3 months after the end of the hospitalization, and to describe the initial clinical presentation and diagnostic modalities in the IE elderly.

Population monitoring: Clinical, therapeutic, biological, microbiological, echocardiographic and geriatric data are collected. (M-2/3 before inclusion; D-15 before inclusion; D0; M3; vital status at 1 year)

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Infective Endocarditis

Eligibility

Sex: ALLMin age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria : * all patients older than 75 years are eligible if they are considered and treated as a case of IE by physicians ensuring their medical care. * the patient should be treated in one of the clinical sites participating at the study. * the patient should benefit during initial hospitalization of a geriatric assessment, in addition to the usual clinical and therapeutic management of such patients. Exclusion criteria : * patients not fulfilling the criteria of definite or possible endocarditis according to Duke modified by Li diagnostic classification that will be applied after collection of all the data at the discharge of the patient.

Locations (1)

Central Hospital - University Hospital

Nancy, France

Outcomes

Primary Outcomes

Change from baseline geriatric characteristics at 3 months

OMS score

Time frame: 3 months after inclusion

Secondary Outcomes

Three months mortality

Mortality rate at 3 months

Time frame: 3 months after inclusion

One year mortality

Mortality rate at 1 year

Time frame: 1 year after inclusion

Change from baseline geriatric characteristics at 3 months

Karnofsky'score

Time frame: 3 months after inclusion

Change from baseline geriatric characteristics at 3 months

Score MNA

Time frame: 3 months after inclusion

Data from ClinicalTrials.gov

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