In this multi-centre randomized controlled trial the investigators compare the effect on dyspnoea severity of oxgen delivery through High Flow Nasal cannula with Low Flow Nasal Prongs in children \< 2 years of age hospitalised for bronchiolitis with moderate-severe dyspnoea.
In this multi-centre randomized controlled trial the investigators compare the effect on dyspnoea severity of oxgen delivery through High Flow Nasal Cannula with Low Flow Nasal Prongs in children \< 2 years of age hospitalised for bronchiolitis with moderate-severe dyspnoea. The study will take place on the pediatric (Non intensive care) units of 5 different hospitals in the Netherlands.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
111
Oxygen delivery through Heated Humidified High Flow Nasal Cannula
Oxygen delivery through Low Flow Nasal Prongs
Isala Klinieken
Zwolle, Overijssel, Netherlands
Amphia
Breda, Netherlands
Deventer Ziekenhuis
Deventer, Netherlands
Medisch Spectrum Twente
Enschede, Netherlands
PEWS (Pediatric Early Warning Score) (in points 0-28)
Sustained reduction in PEWS \>= 2 points within 24 hours (min 0- max 28 points)
Time frame: 24 hours
Comfort (in points 0-10)
(FLACC: Face, Legs, Activity, Cry, Consolability, min 0- max 10 points)
Time frame: 24 hours
ability to feed (yes or no)
need for tubefeeding and/or intravenous fluids
Time frame: 5 days
duration of hospitalisation in days
duration of hospitalisation in days
Time frame: 15 days
admission to PICU (Pediatric Intensive Care Unit) (yes or no)
Time frame: 5 days
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Martini Ziekenhuis
Groningen, Netherlands
Canisius-Wilhelmina Ziekenhuis
Nijmegen, Netherlands
Ikazia Hospital
Rotterdam, Netherlands