Continous Quadratus Lumborum Block for Hepatic Surgery With Right Subcostal Incision

Cui Xulei40 enrolled

Overview

This prospective, randomized study, control study aims to compare the analgesic effect, opioids consumption, quality of recovery, length of hospital stay and et al. between unilateral continuous quadratus lumborum block (QLB) and intravenous patient-controlled analgesia (IPCA) alone in patients undergoing hepatectomy with right J-shape subcostal incision.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

SINGLE

Enrollment

Conditions

Hepatectomy Analgesia Nerve Block

Interventions

Continous QLB (quadratus lumborum block)PROCEDURE

Inject local anesthetics in between quadratus lumborum and psoas major muscle with catheter insertion and continuous local infusion

Philip CX50 Ultrasound ScannerDEVICE

The curved (C1-5) probe of Philip CX 50 Ultrasound Scanner is used for scan

RopivacaineDRUG

* 0.6ml/kg 0.5% ropivacaine with 1:200,000 adrenaline given immediately after the correct position of the tip of the needle has been verified. * followed with 0.2% ropivacaine infusion at a rate of 0.125ml/kg/h given through the catheter inserted in between the quadratus lumborum muscle and psoas major muscle.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-70 yrs * American Society of Anesthesiologists physical statusⅠ-Ⅲ * Undergo hepatectomy with right J-shape subcostal incision * Informed consent Exclusion Criteria: * A known allergy to the drugs being used * Coagulopathy, on anticoagulants * Analgesics intake, history of substance abuse * Participating in the investigation of another experimental agent * Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Locations (1)

Xulei CUI

Beijing, Beijing Municipality, China

Outcomes

Primary Outcomes

Cumulative morphine consumption

Time frame: at 24 postoperative hours

Secondary Outcomes

The pain scores determined by the numeric rating scale (NRS, 0-10)

Time frame: At 0, 2,4, 8, 12, 24 ,48,72 hours and 7 day after the surgery

Nausea and Vomiting score

Time frame: At 0, 2,4, 8, 12, 24 and 48 hours after the surgery

Pruritus score

Time frame: At 0, 2,4, 8, 12, 24 and 48 hours after the surgery

Ambulation time

Time frame: within the 7 days after surgery

Time of recovery of bowl movement

Time frame: within the 7 days after surgery

Quality of recovery

use the self-assessment 11 item QoR scale to assess the patient's recovery quality

Time frame: 3 days and 7 days after surgery

Patient satisfaction with anesthesia

use the Chinese version Bauer questionnaire to assess the patient satisfaction with anesthesia

Time frame: 48 hours after surgery

Postoperative hospital length of stay

Time frame: Up to 6 weeks

Data from ClinicalTrials.gov

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