Monitoring Pre-exposure Prophylaxis for Young Adult Women

Inclusion Criteria: * HIV-uninfected (as determined by Kenya national testing algorithms) * Wanting to start PrEP with an initial recommendation of 6 months of use * Clinically safe to receive PrEP, in accordance with Centers for Disease Control and Prevention (CDC) guidelines: * Creatinine clearance \>60 mL/min * Not infected with hepatitis B * No other medical condition that in the discretion of the site investigator would make participation unsafe or complicate the goals of the study * Sexually active (defined as vaginal or anal sex) within the last 3 months * At high risk for HIV infection based on a validated risk score of \>5 or being in an HIV serodiscordant relationship * Not pregnant * Owns a personal cell phone (not shared) compatible with study protocols and the ability to charge it * Ability to send a text message * Intending to stay in the area for at least the next year * Willing to use study criteria Exclusion Criteria: * Unable to provide consent * Breast-feeding (PrEPis not currently approved for use during breast-feeding) * Concurrent participation in another research study that may influence adherence to PrEP and/or interfere with the procedures of this study.