Multimodal brain monitoring is feasible and can be used in formulating therapeutic strategies during cardiac surgery. Such monitoring may help to improve patient outcome and to reduce costs after cardiac surgery with CPB.
The aim of this study is to use a combination of brain monitoring {Nearinfrared Spectroscopy (NIRS), Transcranial Doppler (TCD), bispectral index (BIS)} to formulate therapeutic strategies based on these monitors and to evaluate the impact on patient outcome.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SCREENING
Masking
TRIPLE
Enrollment
1,200
Patients will be monitored and interference will be done to optimize the medical condition based on such monitor
Patients will be monitored and interference will be done to optimize the medical condition based on such monitor
Patients will be monitored and interference will be done to optimize the medical condition based on such monitor
Faculty of medicine Assiut University
Asyut, Egypt
RECRUITINGS100 protein
S100 protein (marker of brain injury)
Time frame: up to 24 hours
Mini-mental state examination
Time frame: up to 30 days after surgery
Western perioperative neurological scale
Time frame: up to 30 days after surgery
Major neurological out come as stoke
Time frame: up to 30 days after surgery
Duration of mechanical ventilation
Time frame: up to 30 days after surgery
Hospital stay
Time frame: up to 30 days after surgery
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