The Analgesic Efficacy of the Pectoral Block After Mastectomy

Centre Hospitalier Universitaire Vaudois50 enrolled

Overview

Unilateral mastectomy is associated with moderate to severe postoperative pain. A new regional anaesthetic technique has been recently described, call the PEC block. This technique consists of injecting local anaesthetic between different muscles of the chest in order to relieve postoperative pain. The investigators aim to verify that this technique has a clinical relevant postoperative analgesic effect. For that purpose, the investigators will randomise 50 patients scheduled to undergo unilateral mastectomy into two groups: one group will receive a PEC block after the induction of the general anaesthesia under ultrasound guidance, while the other group will not have this regional procedure.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Analgesia

Interventions

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA physical status I-III * Age ≥ 18 * Patients undergoing unilateral mastectomy Exclusion Criteria: * Contraindications to regional block * Pregnancy * Inability to give informed consent * History of alcohol or drug dependence/abuse * History of long term opioid intake or chronic pain disorder

Outcomes

Primary Outcomes

Intravenous morphine consumption during the first 24 postoperative hours (mg)

Time frame: Postoperative day 1

Secondary Outcomes

Intravenous morphine consumption on postoperative day 2 (mg)

Time frame: Postoperative day 2

Intravenous morphine consumption in phase 1 recovery (mg)

Time frame: 2 postoperative hours

Pain scores at rest in phase 1 recovery (visual analogue scale, 0 - 10)

(visual analogue scale, 0 - 10)

Time frame: 2 postoperative hours

Pain scores at rest on postoperative day 1 (visual analogue scale, 0 - 10)

Visual analogue scale, 0 - 10)

Time frame: Postoperative day 1

Pain scores at rest on postoperative day 2 (visual analogue scale, 0 - 10)

Visual analogue scale, 0 - 10)

Time frame: Postoperative day 2

Postoperative nausea and vomiting (yes/no)

Time frame: Postoperative day 1

Postoperative nausea and vomiting (yes/no)

Time frame: Postoperative day 2

Pruritus (yes/no)

Time frame: Postoperative day 1

Pruritus (yes/no)

Time frame: Postoperative day 2

The Analgesic Efficacy of the Pectoral Block After Mastectomy

Overview

Conditions

Interventions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Secondary Outcomes