NCT02917824 - Intensity, Specificity and Reversibility of Inspiratory Muscle Training in Asthmatics | Crick | Crick

Intensity, Specificity and Reversibility of Inspiratory Muscle Training in Asthmatics

N/ACompletedNCT02917824

Universidade Federal do Rio Grande do Norte29 enrolled

Overview

Inspiratory muscle training (IMT) can reverse or delay the complications from the deterioration of inspiratory muscle function in asthma. Thus, the IMT has been considered a treatment option for people with asthma. The aim of this study is to investigate the training principles of intensity, specificity and reversibility of IMT in asthmatics.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

29

Conditions

Interventions

High-intensity IMTDEVICE

30 breaths at 50% of the maximal inspiratory pressure, twice daily for 6 weeks

Low-intensity IMTDEVICE

30 breaths at 15% of the maximal inspiratory pressure, twice daily for 6 weeks

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of asthma * Adults (18 - 60 years) Exclusion Criteria: * Inability to perform the protocol established by the study * Others respiratory diseases * Request for study withdrawal

Locations (1)

Gardenia Maria Holanda Ferreira

Natal, Rio Grande do Norte, Brazil

Outcomes

Primary Outcomes

Change in inspiratory muscle strength

Maximal inspiratory pressure

Time frame: Baseline, 6 weeks later and 6 weeks after training

Change in expiratory muscle strength

Maximal expiratory pressure

Time frame: Baseline, 6 weeks later and 6 weeks after training

Secondary Outcomes

Change in asthma control

Asthma Control Questionnaire measures the adequacy of asthma control and change in asthma control which occurs either spontaneously or as a result of treatment. Scores range between 0 (totally controlled) and 6 (severely uncontrolled)

Time frame: Baseline, 6 weeks later and 6 weeks after training

Change in quality of life

Asthma Quality of Life Questionnaire is a disease-specific health-related quality of life instrument that taps both physical and emotional impact of disease. Scores range 1-7, with higher scores indicating better quality of life.

Time frame: Baseline, 6 weeks later and 6 weeks after training

Change in six minute walk test distance

Six-minute walk test (6MWT)

Time frame: Baseline, 6 weeks later and 6 weeks after training

Change in forced vital capacity

Forced vital capacity in litres and % of predicted

Time frame: Baseline, 6 weeks later and 6 weeks after training

Change in forced expiratory volume

Forced expiratory volume in litres and % of predicted

Time frame: Baseline, 6 weeks later and 6 weeks after training

Data from ClinicalTrials.gov

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