Phase I clinical trial to evaluate safety of FURESTEM-CD Inj. in patients with moderate to severe in plaque-type psoriasis injection for 4weeks.
This is a phase 1, single center, randomized, open label, study of safety of FURESTEM-CD Inj. in subjects with moderate to severe plaque psoriasis. Approximately 9\~18 subjects will be administrated FURESTEM-CD Inj. FURESTEM-CD Inj. is composed of allogeneic hUCB-MSC(human Umbilical Cord Blood derived-Mesenchymal Stem cell). hUCB-MSCs are mesenchymal stem cells from umbilical cord blood. Mesenchymal stem cells are well-known for immunosuppression, anti-inflammatory ability and capable of differentiating into a wide range of cell types. Therefore, FURSTEM-CD Inj. has huge possibility as cell therapy products for plaque-type Psoriasis patients.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
9
Patients will be treated FURESTEM-CD Inj. Subcutaneous injection
The Catholic Univ. Korea Seoul, St. Marry's Hospital
Seoul, South Korea
RECRUITINGnumber of adverse events
Time frame: 4 weeks follow-up after treatment
safety lab tests, physical examination, ECG, vital signs
Time frame: 4 weeks follow-up after treatment
variation of Cytokine, PASI, BSA
Time frame: 4 weeks follow-up after treatment
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