Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 4 of 7)

N/ACompletedNCT02919228

University of Bern50 enrolled

Overview

NOTE: This is the fourth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674. This sub-study includes 50 participants and 8 arms, in total 350 participants will be assessed in all 7 sub-studies. General study information: This is a randomized, cross-over, quantitative study, which investigates physiological variables, mood, and affect of healthy participants in response to colored light exposure. The Participants take part in 5-8 arms and are exposed to colored light only, or are additionally asked to solve cognitive tasks during the colored light exposure. Primary aim is to measure the change in several physiological variables, mood, and affect during colored light exposure of 15 or 45 minutes. The risk for the participants is negligible and comparable to the risk during daily life.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Exposure to Man-made Visible Light

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Normal color vision * Right handed * Written informed consent Exclusion Criteria: * Smoking * Any kind of diagnosed sleep disorder or neurological or psychiatric disorder in the last 3 months * Acute severe traumas * Chronic diseases with the necessity for medication * Use of recreational drugs * Regular intake of medication that would affect the outcome measures * Regular excessive alcohol use (\> 18 standard units / week) * Transmeridian travel in the last month (crossed \> 1 time zone border) * Night shift word during the last month

Outcomes

Primary Outcomes

Change in cerebral tissue oxygen saturation during colored light exposure compared with a baseline and a recovery period