Bone Marrow Micrometastases in Patients With Early Stage Breast Cancer

Inclusion criteria: 1. Patients over 18 years old and who have given informed consent to enter the study. 2. ASA I-II patients 3. Patients who have not been diagnosed as breast cancer or received any type of treatment regarding breast cancer before the time of study 4. Patients who are appropriate for bone marrow biopsy 5. Menopausal status is not relevant. Exclusion criteria: 1. Active collagen tissue disorders 2. Patients who are diagnosed having breast cancer and received any type of treatment regarding breast cancer before the time of study 3. Pregnancy 4. Patients with bleeding disorders, who are receiving antiaggregant or anticoagulant medication. 5. Patients who refused to enter the study protocol and refused to give informed consent.