The aim of this study is early tracheotomy to facilitate weaning by switching between invasive and noninvasive ventilation.
When a patient is eligible to this study, he or she is randomly assigned to intervention or control group.In intervention group,tracheotomy is performed. And then, patient is switched to noninvasive ventilation by masking the tracheotomy tube. If the patient presents distress in noninvasive ventilation, he or she is switched to invasive ventilation. If the distress relieves, patient is switched to noninvasive ventilation again until the patient successfully weans from ventilator. In control group, the patient is weaned as the conventional methods.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
As defined criteria, patients are switched between invasive and noninvasive ventilation until the ventilator is successfully weaned.
The first affiated hospital, chongqing medical university
Chongqing, Chongqing Municipality, China
RECRUITINGventilator weaning days
Time frame: from enrollment to 90 days
successful weaning rate
Time frame: from enrollment to 90 days
ICU stay days
Time frame: from admission to 90 days
hospital stay days
Time frame: from admission to 90 days
ICU mortality
Time frame: from admission to 90 days
hospital mortality
Time frame: from admission to 90 days
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