Study to Determine the Effect of the Timing of a Meal on the Pharmacokinetics of Entinostat

Inclusion Criteria: * Healthy adults 19-55 years of age at screening. * Continuous non-smoker who has not used nicotine-containing products for at least 3 months prior to first dose and throughout the study. * Body mass index of ≥ 18.5 at screening. * Medically healthy with no significant medical history, physical examination, laboratory values, vital signs, or ECGs. Liver function tests and serum bilirubin must be ≤ the upper limit of normal. Platelets, hemoglobin, and hematocrit must be \> the lower limit of normal at screening. * Females of non-childbearing potential must have undergone sterilization procedures as noted in protocol at least 6 months prior to dose. * Non-vasectomized male subjects must agree to use a condom with spermicide or abstain from sexual intercourse during the study until 90 days beyond dose of study drug. * Male subjects must agree not to donate sperm from the first dose until 90 days beyond dose of study drug. * Understands the study procedures in the informed consent form and be willing and able to comply with the protocol. Exclusion Criteria: * Mentally or legally incapacitated or has significant emotional problems at screening or expected during the conduct of the study. * History or presence of clinically significant medical or psychiatric condition or disease in the opinion of the PI or designee. * History of illness that might confound the results of the study or poses an additional risk to the subject by their participation in the study in the opinion of the PI or designee. * History of presence of alcoholism or drug abuse within the past 2 years prior to dose. * History or presence of clinically significant cancer, cardiovascular disorders, acute or chronic gastrointestinal conditions in the opinion of the PI. * Females of childbearing potential. * Females with a positive pregnancy test or lactating. * Positive urine drug or alcohol results are screening or each check-in. * Positive urine cotinine at screening. * Positive results are screening for HIV, hepatitis B surface antigen, or hepatitis C virus * Seated blood pressure is less than 90/40 mmHg or greater than 140/90 mmHg at screening. * Seated heart rate lower than 40 bpm or higher than 99 bpm at screening. * QTcB interval (correction value of the interval between the Q and T waves on the ECG tracing using the Bazett Correction Formula) \> 460 msec for males or \> 480 msec for females or has ECG findings deemed abnormal by the PI or designee. * Estimated creatinine clearance \< 90 mL/min at screening. * Unable to refrain from or anticipates the use of any prescription or non-prescription medications and any drugs known to be significant inhibitors or CYP (Cytochromes 450) enzymes and/or P-gp. * Has been on a diet incompatible with the on-study diet within 28 days prior to dose and throughout the study in the opinion of the PI or designee. * Is lactose intolerant. * Donation of blood or significant blood loss within 56 days prior to dose. * Plasma donation within 7 days prior to dose. * Participation in another clinical study 28 days prior to dose.