The purpose of this study is to determine the safest and most effective flushing solution for maintaining patency (unobstructed flow) in BioFlo implanted port catheters. The complication rate in patients whose ports are flushed with saline only will be compared to the complication rate in patients whose ports are flushed with a combination of saline and heparinized saline.
The purpose of this study is to determine the safest and most effective flushing solution for maintaining patency (unobstructed flow) in BioFlo implanted port catheters. The complication rate in patients whose ports are flushed with saline only will be compared to the complication rate in patients whose ports are flushed with a combination of saline and heparinized saline. These complications include partial or complete obstruction, infection of the central line, and/or the onset of heparin induced thrombocytopenia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
28
The control group will have their port catheters flushed with 20mL saline + 5mL heparin 100 units/mL; q 3 months
The intervention group will have their port catheters flushed with saline only.
TriHealth Cancer Institute Good Samaritan Infusion Center at GSH
Cincinnati, Ohio, United States
Ambulatory Treatment Center at Bethesda North TriHealth Hospital
Cincinnati, Ohio, United States
TriHealth Cancer Institute Good Samaritan Infusion Center, Medicenter
Cincinnati, Ohio, United States
TriHealth Cancer Institute Good Samaritan Infusion Center, Cheviot
Number of Participants With Occurrence of First Complete Occlusion (Blockage)
Number of Participants with Occurrence of First Complete Occlusion (Blockage) over the 1 year. The date of the first complete occlusion will be recorded.
Time frame: baseline to 1 year
Number of Participants With Occurrence of First Partial Occlusion (Blockage)
Number of Participants with Occurrence of First Partial Occlusion (Blockage) within the 1 year. The date of the first partial occlusion will be recorded.
Time frame: baseline to 1 year
Number of Participants Who Required CathFlo (Alteplase) to Resolve an Occlusion
Number of Participants who required CathFlo (alteplase) to resolve an Occlusion over the 1 year. The date of first CathFlo administration will be recorded.
Time frame: baseline to 1 year
Number of Complete or Partial Occlusions
The number of complete or partial occlusions after the first occurrence will be recorded.
Time frame: baseline to 1 year
Number of Days Catheter Remains Patent (Unobstructed)
The number of days from study enrollment to the first partial or complete occlusion and the number of days between incidences of partial or complete occlusion will be recorded.
Time frame: baseline to 1 year
Central Line-Associated Blood Stream Infection (CLABSI)
Any laboratory-confirmed blood stream infection that is considered central line associated will be recorded.
Time frame: baseline to 1 year
Heparin-related Complication
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Cincinnati, Ohio, United States
TriHealth Cancer Institute Good Samaritan Infusion Center, Anderson
Cincinnati, Ohio, United States
TriHealth Cancer Institute Good Samaritan Infusion Center Butler County
Hamilton, Ohio, United States
Heparin Induced Thrombocytopenia (HIT) as measured by a positive HIT antibody test, or any other heparin allergy, will be recorded.
Time frame: baseline to 1 year