Metabolic Effects of Egg Protein and Unsaturated Fat Intakes in Subjects With Hypertriglyceridemia

Inclusion Criteria: * Fasting TG level 150-499 mg/dL * Body mass index (BMI) 25.0-39.9 kg/m2 * Score of 7-10 on Vein Access Scale * Normally active and judged to be in general good health on basis of medical history and routine laboratory tests Exclusion Criteria: * Fasting blood glucose ≥126 mg/dL or known type 1 or type 2 diabetes mellitus * Atherosclerotic cardiovascular disease * Recent history or current significant renal, pulmonary, hepatic, biliary, or gastrointestinal disease * Abnormal lab test results of clinical significance (e.g., creatinine ≥1.5 mg/dL and aspartate or alanine transaminase ≥1.5 times upper limit of normal) * History of cancer in previous 2 years * Uncontrolled hypertension * Recent unstable use of anti-hypertensive medication, thyroid hormone replacements, and/or medications known to substantially influence carbohydrate metabolism * Recent use of certain blood pressure medications (e.g., beta-adrenergic blockers and/or high-dose thiazide diuretics) * Recent use of lipid-altering drugs (e.g., statins, bile acid sequestrants, cholesterol absorption inhibitors, or fibrates) * Recent use of diabetes medication (e.g., alpha-glucosidase inhibitors, biguanides and biguanide combinations, bile acid sequestrants, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, meglitinides, and sulfonylureas and combination sulfonylureas) * Recent use of lipid-altering foods, herbs, or dietary supplements (e.g., niacin, sterol/stanol products, dietary fiber supplements, red rice yeast supplements) * Recent unstable use of herbs and dietary supplements that may influence carbohdyrate metabolism * Extreme dietary habits, dietary restrictions, or significant food allergies * Required energy intake \<2200 kcal/day or \>3400 kcal/day * Recent change in body weight of ±4.5 kg * Recent use of weight loss drugs or programs * Active infection or on antibiotic therapy * Current or recent history of drug or alcohol abuse * Pregnant, planning to be pregnant, or lactating females or women of childbearing potential unwilling to commit to use of a medically approved form of contraception