Psychophysical Characterization and Brain Correlates of Dentine Hypersensitivity

University of Zurich30 enrolled

Overview

Up to date, devices capable of delivering controlled, calibrated, non-contact cold air stimuli in a MR environment are unavailable for quantitative sensory testing. This project therefore aimed at designing and constructing a novel MR-compatible, computer-controlled cold air stimulation device that produces air puffs in a broad flow and cold temperature range. By means of this device, detailed psychophysically testing and subsequent brain scanning of dentine hypersensitivity (DH) subjects will be possible to gain new insights about DH mechanisms.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Dentine Hypersensitivity

Interventions

air puffsOTHER

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age and between 18 - 60 Exclusion Criteria: * Caries * Defective restorations * Full crowns * Orthodontic bands * Bleeding on probing and periodontal pockets deeper than 3 mm * Subjects with gross periodontal disease or treatment of periodontal disease in the past 12 months.

Locations (1)

University of Zurich, Center of Dental Medicine

Zurich, Switzerland

Outcomes

Primary Outcomes

Subjective ratings using the BORG scale

individual subject perception ratings will be recorded by means of an adapted BORG scale. For reliability, intraclass correlations will be used covering 3-4 measures within a 3-4-weeks period.

Time frame: May 1, 2016

blood oxygenation level dependent (BOLD) response

Changes in blood oxygenation level (indirect measure of neural activity) will be recorded

Time frame: October 1, 2016

Data from ClinicalTrials.gov

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