Effects of Different Area of Internal Limiting Membrane Peeling (ILM) Peeling on Anatomical Outcomes in Macular Hole Surgery

Peking University People's Hospital128 enrolled

Overview

The purpose of this study is to determine the effects of two different internal limiting membrane (ILM) peeling area on anatomical closure outcomes after macular hole surgery measured by optical coherence tomography (OCT).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

128

Conditions

Macular Hole

Interventions

ILM peeling surgeryPROCEDURE

4PD or 2PD diameter of ILM peeling in surgery was given to patients with idiopathic macular hole (IMH)

Eligibility

Sex: ALLMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients with IMH * patients signed the informed consent form (ICF) * patients with course of IMH less than 3 years Exclusion Criteria: * patients with hyper myopia * patients with traumatic macular hole * accompanied or secondary of other fundus disease * open or reopen after receiving MH surgery * patients with retinal detachment * received vitrectomy due to other diseases * glaucoma cannot be controled by medication * patients with other retinal or choroidal disease that may affect VA * poor patients compliance * poor condition that cannot undertake the surgery * dioptric media opacities which make it difficult to exam fundus or measure on OCT

Outcomes

Primary Outcomes

Anatomical closure grades in OCT

Time frame: 1 year

Secondary Outcomes

Change of anatomical closure grades in OCT

Time frame: 3 months, 6 months, 1 year

Change from baseline in BCVA (best corrected visual acuity)

Time frame: 3 months, 6 months, 1 year

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.