Major abdominal surgeries are associated with severe abdominal pain, which can affect respiratory and cardiac functions, if insufficiently managed. This increases the incidence of post-operative morbidity. The objective of this study was to detect the efficacy and safety of magnesium sulphate as an adjuvant to the analgesia offered by local anesthetic in ultrasound guided TAP block in patients undergoing total abdominal hysterectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
60
ultrasound guided TAP block with 20 mL of 0.25% bupivacaine plus 2 mL magnesium sulfate 10% (200 mg), on each side of the abdominal wall.
ultrasound guided TAP block with 20 mL of 0.25% bupivacaine on each side of the abdominal wall.
total postoperative morphine consumption
total amount of rescue morphine consumption in the first 24 hours postoperatively
Time frame: postoperative 24 hours
postoperative pain
postoperative pain measured by VAS score recorded in the first 24 hours postoperatively
Time frame: postoperative 24 hours
first request of rescue analgesia
time to the first requirement of rescue analgesia during the first 24 hours postoperatively
Time frame: postoperative 24 hours
side effects
occurrence of side effects during the first 24 hours postoperatively
Time frame: postoperative 24 hours
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