Chronic knee osteoarthritis (OA) is one of the most common diseases with increasing prevalence in advanced age. Knee OA results in movement restriction, sleep disturbance, and disability. Total knee arthroplasty (TKA) is employed often in the symptomatic treatment of knee OA. It has been estimated that 3.4 million TKAs will be performed in the year 2030 in the United States alone. Many studies report rewarding outcomes for patients, but other research shows there are many patients that remain dissatisfied post-arthroplasty. The purpose of this study is to evaluate whether genicular radiofrequency ablation can relieve chronic post-arthroplasty knee pain.
Chronic knee osteoarthritis (OA) is one of the most common diseases with increasing prevalence in advanced age. Knee OA results in movement restriction, sleep disturbance, and disability. Total knee arthroplasty (TKA) is employed often in the symptomatic treatment of knee OA. It has been estimated that 3.4 million TKAs will be performed in the year 2030 in the United States alone. Many studies report rewarding outcomes for patients, but other research shows there are many patients that remain dissatisfied post-arthroplasty. As the prevalence of knee arthroplasty increases, so does the frequency of revisions. It has been found that 20% of patients reporting painful knee arthroplasties were not able to be diagnosed with a specific cause and were therefore referred to a pain specialist. Pharmacologic therapy and non-surgical interventions are often employed with minimal benefit to the patient's level of disability as indicated by clinical evidence. Genicular radiofrequency ablation seems to be a safe, effective and minimally invasive therapy for chronic knee OA patients who have had a positive diagnostic block. No study has determined whether genicular radiofrequency ablation can relieve chronic post-arthroplasty knee pain. The investigators propose to examine the effect of genicular radiofrequency ablation in chronic post-arthroplasty knee pain in patients who respond positively to diagnostic nerve blocks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
9
Ablation of the genicular nerves of the knee by radiofrequency
Genicular radiofrequency of the knee without neurotomy
WK River Cities Clinical Research Center
Shreveport, Louisiana, United States
Mean difference in knee pain intensities as indicated on the Visual Analog Scale
Time frame: Baseline and 6 weeks post-radiofrequency ablation
Change in Visual Analog Score of average knee pain
Time frame: Baseline to 1 week, 6 weeks, and 12 weeks
Change in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
Time frame: Baseline to 1 week, 6 weeks, and 12 weeks
Change in Knee Injury and Osteoarthritis Outcome Score (KOOS)
Time frame: Baseline to 1 week, 6 weeks, and 12 weeks
Change of Patient Global Assessment
Time frame: Baseline to 1 week, 6 weeks, and 12 weeks
Satisfaction with Radiofrequency Procedure
Time frame: Baseline to 1 week, 6 weeks, and 12 weeks
Rate of procedure-related Adverse Events
Time frame: From informed consent through study completion, up to 20 weeks
Rate of Serious Adverse Events
Time frame: From informed consent through study completion, up to 20 weeks
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