Application of Mechanical Cardiopulmonary Resuscitation Devices and Their Value in Out-of-hospital Cardiac Arrest: A Retrospective Analysis of the German Resuscitation Registry

German Resuscitation Registry19,609 enrolled

Overview

The aim of this study was to analyse a large CPR database, the German Resuscitation Registry, to evaluate potential benefits of mechanical CPR devices over manual CPR in adult cardiac arrest victims. The primary endpoint considered is ROSC.

In a retrospective analysis of the German Resuscitation Registry between 2007-2014, investigators examined the outcome after using mechanical CPR on return of spontaneous circulation (ROSC) in adults with out-of-hospital cardiac arrest (OHCA). Investigators compared mechanical CPR (Intervention group) to manual CPR (control group). According to preclinical risk factors, investigators calculated the predicted ROSC-after-cardiac-arrest (RACA) score for each group, and compared it to the rate of ROSC observed. Using multivariate analysis, investigators adjusted the influence of the devices' application on ROSC for epidemiological factors and therapeutic measures.

Study Type

OBSERVATIONAL

Enrollment

19,609

Conditions

Out-of-hospital Cardiac Arrest

Interventions

mechanical chest compression deviceDEVICE

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * out of hospital cardiac arrest * during time prod from January 2007 until December 2014 * CPR attempted Exclusion Criteria: * Investigators excluded cases in which CPR was continued for less than five minutes, or duration of CPR was missing, as the outcome in this early period is not affected by the CPR mode. * Children aged less than 18 years and patients of unknown age were also excluded as the devices are not approved for resuscitation on children. * An active compression-decompression (ACD) is a hand-held suction device, to compress and actively decompress the chest after each compression. * Investigators also excluded cases where ACD CPR was used, because it constitutes a different technology. * Cases due to trauma were excluded as application of mechanical CPR devices may be limited due in traumatic events. * Cases where data on ROSC and/or CPR mode was missing were also excluded.

Outcomes

Primary Outcomes

return of spontaneous circulation

sustained return of spontaneous circulation at any time during CPR

Time frame: sustained ROSC at any time latest after 24 hours

Data from ClinicalTrials.gov

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