The purpose of this study is to explore the effect of G-CSF combination with GM-CSF on prevention and treatment of infection in children with malignant tumor.
G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
405
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic CSFs that decrease the duration and severity of neutropenia for patients receiving chemotherapy. GM-CSF is a stimulator of the growth and differentiation of hematopoietic progenitor cells committed to neutrophils, monocytes or eosinophils.
Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic CSFs that decrease the duration and severity of neutropenia for patients receiving chemotherapy. G-CSF is a relatively specific stimulator of the growth and differentiation of hematopoietic progenitor cells committed to the neutrophil lineage.
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) are hematopoietic CSFs that decrease the duration and severity of neutropenia for patients receiving chemotherapy. GM-CSF and G-CSF share a number of biologic activities, GM-CSF seems to be more potent against fungi.
The First Affiliated of Xiamen University
Xiamen, Fujian, China
RECRUITINGChildren's Hospital of Soochow University
Suzhou, Jiangsu, China
RECRUITINGShandong Province Qianfoshan Hospital
Jinan, Shandong, China
assess the incidence of infection in patients after chemotherapy
Time frame: within 20 days after chemotherapy
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China
RECRUITINGChildren's Hospital of Fudan University
Shanghai, Shanghai Municipality, China
RECRUITINGXinhua Hospital affiliated to Shanghai Jiaotong University school of medicine
Shanghai, Shanghai Municipality, China
RECRUITINGNorthwest Women's Hospital
Xi'an, Shangxi, China
RECRUITING