Venous thromboembolism (VTE) is an important cause of post-operative morbidity and mortality in women undergoing surgery for gynecologic malignancies. Although the benefit of thromboprophylaxis in reduction of post-operative VTE events after surgery for gynecologic cancers has been well documented around the world, the evidence for Chinese women is rare. The investigators designed this prospective and randomized study to assess the benefit of pharmacologic prophylaxis for patients received surgical treatment for gynecologic malignancies in China.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
315
2125KU, subcutaneous injection of 5-10 days
4250KU, subcutaneous injection of 5-10 days
20mg, injection for 5-10 days
Tongji Hospital
Wuhan, Hubei, China
VTE rate
Time frame: 30-days from the date of operation
Bleeding rate
Time frame: 30-days from the date of operation
Infection rate
Time frame: 30-days from the date of operation
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