Osteoporosis is a serious global health problem, second only to cardiovascular disease. Osteoporosis is the most common metabolic bone disease in the elderly population, characterized by loss of bone mineral density (BMD) and continuous destruction of bone microstructure, especially in postmenopausal women. It gives rise to bone fragility and fracture risk. Moreover, as people grow older, falls frequently occur with high severity, and nearly 35% to 45% of persons aged 65 or older fall at least once a year. Osteoporotic fractures increase mortality, morbidity, chronic pain, and the cost of social care and it decreases the quality of life. Here, investigators plan to perform different exercise interventions such as circuit exercise, aerobic dance and Tai Chi on the community's older adults to evaluate whether exercise intervention could improve the bone mineral density, physical fitness, muscle strength or quality of life.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
411
circuit exercise, aerobic dance and Tai Chi exercise
Sports Medicine Center, Chang Gung Memorial Hospital
Pizi, Taiwan
Change from baseline bone mineral density
Bone mineral density measurement is measured by dual-energy x-ray absorptiometry (DXA). Measurements are made over the lumbar spine and over the upper part of the hip and the measurement is assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Change from baseline elbow muscle strength
Extension and flexion of elbow were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Change from baseline shoulder muscle strength
Extension and flexion of shoulder were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Change from baseline hip muscle strength
Extension and flexion of hip were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Change from baseline knee muscle strength
Extension and flexion of knee were tested by the HUMAC NORM system (CSMi, Stoughton, MA) with the eccentric/concentric contraction mode at an angular velocity of 60 degrees/s.Isokinetic tests were performed five times for each participant, and each test was separated by a rest period of 3 min.The Muscle strength was present as a peak torque which was normalized to body weight (Unit:Nm/kg). The participants are assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Change from baseline SF-36 questionnaire assessment
SF-36 consists of eight scaled scores, which are the weighted sums of the questions in their section. Each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. The lower score the more disability. The higher the score the less disability. Eight sections including physical function, role limitation due to physical problems, bodily pain, general health, vitality, social functioning, role limitation due to emotional problems, and mental health. Additionally, the eight health domains can be used to provide a physical component summary and mental component summary score. The outcome measurement is assessed at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
High-density lipoprotein from blood sample
High-density lipoprotein are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Triglyceride from blood sample
Triglyceride are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Fasting blood glucose from blood sample
Fasting blood glucose are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Blood pressure
Diastolic and systolic blood pressure are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Weight parameters of the subjects
Weight (kg) are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Height parameters of the subjects
Height (cm) are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
Waistline parameters of the subjects
Waistline (cm) are measured at Pre-intervention, 3-month, 6-month, 9-month-follow-up.
Time frame: Pre-intervention, 3-month, 6-month, 9-month-follow-up
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