Intranasal Desmopressin vs IV Ketorolac in Renal Colic Pain Control

Shahid Beheshti University of Medical Sciences40 enrolled

Overview

The aim of this study is the comparison of efficacy of intravenous ketorolac and intranasal desmopressin in renal colic patients pain control.

40 renal colic patients have been divided into 2 groups randomly, one group has been received 30mg intravenous Ketorolac and 4 puffs nasal Normal Saline while other has been received 40 micrograms nasal Desmopressin and 1cc intravenous Normal Saline. Pain Score before drug administration,also 10, 30 and 60 minutes after drug administration has been measured bye Visual Analogue Scale ( VAS ).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Renal Colic

Interventions

DesmopressinDRUG

40 micrograms Nasal Desmopressin.

KetorolacDRUG

30mg intravenous Ketorolac.

Normal SalineDRUG

1cc intravenous Normal Saline.

Normal Saline

Eligibility

Sex: ALLMin age: 16 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * renal colic patients Exclusion Criteria: * history of hypertension and cardiac disease * pregnant patients * use of analgesic within 4 hours before intervention

Outcomes

Primary Outcomes

Pain score

Time frame: Pain score change from baseline pain score before intervention 10, 30 and 60 minutes after intervention

Data from ClinicalTrials.gov

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