The T-REX study aims to clarify the actual status of metastatic lymph node (LN) distribution in colon cancer and provide reliable evidence regarding the optimal length of bowel resection and the extent of central lymph node dissection in colon cancer surgery.
In colon canser, the incidence of metastasis in the pericolic lymph nodes (LNs) located along the bowel and marginal artery is high. The optimal extent of bowel resection is closely associated with how we define 'regional' pericolic LNs, which should be resected because of the risk of metastasis. However, there are no standardised criteria for 'regional' LNs in the pericolic area. To establish a consensus for the extent of bowel resection and appropriate central LN dissection, international prospective stdies focusing on the distribution of metastatic LNs along the bowel and the primary feeding artery are conducted.
Study Type
OBSERVATIONAL
Enrollment
3,647
Distribution of metastatic LNs
Time frame: At the time of patient registry in
Distribution of metastatic LNs
Time frame: At the time of 4 years after surgery
Prognostic outcomes according to the length of bowel resection
Time frame: 4 years
Prognostic outcomes according to the central radicality
Time frame: 4 years
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University Hospital Erlangen
Erlangen, Bavaria, Germany
Aichi Cancer Centre Hospital
Nagoya, Aichi-ken, Japan
Fujita Health University
Toyoake, Aichi-ken, Japan
National Canser Centre Hospital East
Chiba, Chiba, Japan
Teikyo University Chiba Medical Center
Ichihara-shi, Chiba, Japan
Keiyukai Sapporo Hospital
Sapporo, Hokkaido, Japan
Kurume University School of Medicine
Kurume, Hukuoka-prefecture, Japan
Yokohama City University Medical Center
Yokohama, Kanagawa, Japan
Saisei-kai Yokohama-shi Nanbu Hospital
Yokohama, Kanagawa, Japan
Yokohama-city University
Yokohama, Kanagawa, Japan
...and 26 more locations