Effect of Anthocyanins Extracted From Purple Potatoes on Healthy Study Subjects' Postprandial Glycemia and Insulinemia

University of Turku18 enrolled

Overview

A randomized, single-blind cross-over clinical nutrition trial will be conducted. The effects of yellow-fleshed potatoes and yellow-fleshed potatoes supplemented with anthocyanins extracted from purple-fleshed potatoes on healthy men's postprandial glycemia and insulinemia will be compared. Additionally, the postprandial metabolism and metabolites, and the appearance and metabolism of the flavonoids and their metabolites is studied in plasma, urine and feces.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Postprandial Glycemia

Interventions

DietaryOTHER

Eligibility

Sex: MALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-45 * Male * No regular medication * No participation in a drug trial or blood donation within 2 months * Non-smoker * Signs informed consent * Body mass index 18.5-27 kg/m2 * Fasting plasma cholesterol \< 5.5 mmol/l * Fasting plasma triacylglycerols \< 2.6 mmol/l * Fasting plasma glucose 4-6 mmol/l * blood pressure \<140/80 mmHg * hemoglobin\>130 g/l * Fasting plasma alanine amino transferase (ALAT) \<60 U/l (normal liver function) * Fasting plasma thyroid-stimulating hormone (TSH) 0.4 - 4.5 mU/l (normal thyroid function) * Fasting plasma creatinine \<118 µmol/l (normal kidney function) Exclusion Criteria: * Regular smoking * Alcohol abuse * Regular medication

Locations (1)

Department of Biochemistry, University of Turku

Turku, Finland