The aim of this study to assess effect of ketorolac premedication on the effectiveness of the inferior alveolar nerve block, pretreatment and postoperative pain in patients with symptomatic irreversible pulpitis.
* Patients will be clinically and radiographically examined and their eligibility will be assessed and preoperative pain will be measured. Eligible patients will be treated in one visit. * Patients will be randomly assigned to one of 2 groups: experimental group (taking a 10 mg tablet of ketorolac) and the control group (taking a placebo tablet). Each tablet will be taken one hour before starting treatment. The patient's pain will be assessed before local anesthetic adminstration. After 15 minutes of the initial inferior alveolar nerve block (IANB), the teeth will be examined using a cold pulp sensitivity test; in case of no or mild pain, the treatment will be initiated. * During root canal treatment, no to mild pain response will be considered success. In case of failure, supplemental anesthesia will be administrated. * Postoperative pain will be assessed 6, 12, 24 and 48 hours after treatment. The number of patients who will require rescue analgesic medication within the 48 hours postoperatively will be counted.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
38
A 10 mg tablet of the medication will be given one hour before starting the root canal treatment
The placebo given as a tablet one hour before staring the root canal treatment
Anesthetic efficiency
Pain during endodontic treatment will be assessed using a numerical rating scale (NRS). No or mild pain response will be considered success.
Time frame: Intraoperative (During endodontic treatment)
Postoperative pain
Postoperative pain will be measured using a numerical rating scale (NRS)
Time frame: At 6,12, 24, 48 hours after root canal treatment
Number of patients requiring rescue analgesic.
Number of patients requiring rescue analgesic within 48 hours after endodontic treatment
Time frame: Within 48 hours after endodontic treatment
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