The Impact of Botulinum Toxin on Brow Height and Morphology: A Randomized Controlled Trial

St Joseph University, Beirut, Lebanon30 enrolled

Overview

The purpose of this study is to describe three safe and reproducible techniques for brow lifting using botulinum toxin. It will also describe the effect of 2 techniques on the eyebrow shape using quantitative, objective measurements and satisfaction scales.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Brow Lifting

Interventions

DysportDRUG

lateral orbicularis injectionPROCEDURE

Lateral orbicularis + corrugator injectionPROCEDURE

Eligibility

Sex: FEMALEMin age: 28 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Consecutive 30 female patients presenting to our clinic for brow lifting with botulinum toxin will be randomized to receive one of the two injection techniques Exclusion Criteria: * Patients with previous periorbital/forehead surgery * Patients who plucked the upper eyebrow margin * Patients with eyebrow tatoos * Patients with upper face botulinum toxin injection in the past 12 months * Patients with resorbable upper face fillers injection in the past 12 months * Patients with previous permanent upper face fillers injection * Pregnant patients * Lactating patients * Patients with preexisting neuromuscular conditions (myasthenia gravis, Eaton Lambert syndrome) * Patients using medication that could potentiate the effect of botulinum (ex: aminoglycoside antibiotics) * Patients with sensitivity to botulinum toxin or human albumin

Locations (1)

Hotel Dieu De France

Beirut, Aschrafieh, Lebanon

RECRUITING

Outcomes

Primary Outcomes

Objective assessment

Objective assessment will be done on anteroposterior views of pre-and-post injection photographs. The mid pupillary line will be drawn and the eyebrow vertical height will be measured from this line to the upper border of the brow at seven horizontal points: the most medial aspect of the eyebrow, medial canthus, medial limbus, mid pupil, lateral limbus, lateral sclera, and most lateral eyebrow.

Time frame: 15 days post treatment

Secondary Outcomes

Patient satisfaction

Patient satisfaction will be determined by a questionnaire completed at 15 days post-treatment. Subjects will indicate how satisfied they are on a 4-point scale (1-4) as follow: 1. Very Satisfied 2. Satisfied 3. Dissatisfied 4. Very Dissatisfied.

Time frame: 15 days post treatment

Data from ClinicalTrials.gov

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