A Comparison of Three Nutritional Assessment Methods Predicting Prognosis in COPD With Respiratory Failure

West China Hospital750 enrolled

Overview

This is a retrospective study of patients diagnosed with chronic obstructive pulmonary disease (COPD) with respiratory failure and admitted in West China Hospital during January 2014 to March 2016 by review of medical records. The following variables will be retrospectively studied: age, sex, marriage, height, weight, respiratory rate, PaO2, PaCO2, nutritional risk screening 2002 (NRS 2002) score, ALB, short-term and long-term prognostic outcomes, and so on. The purpose of this study is to compare the predictive power of three widely used nutritional assessment methods (BMI, NRS 2002 and ALB) predicting the prognostic outcomes in a cohort of COPD patients with respiratory failure.

Study Type

OBSERVATIONAL

Enrollment

750

Conditions

Pulmonary Disease, Chronic Obstructive Respiratory Insufficiency

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Newly diagnosis of COPD at West China Hospital during January 2014 to March 2016 * Partial pressure of O2 (PaO2) \< 60 mmHg and/or partial pressure of CO2 (PaCO2) \>50 mmHg * Age ≥ 18 years * Respiratory rates \> 23 bpm Exclusion Criteria: * Pregnancy or during lactation * Ventilatory dysfunction due to neuromuscular disorders, acute and chronic thromboembolic disease, severe illness in other systems * Incomplete medical profiles

Locations (1)

Outcomes

Primary Outcomes

Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of in-hospital death

Time frame: up to 27 months

Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 1-year death after discharge

Time frame: up to 27 months

Predictive value of nutritional assessment methods in identifying COPD patients with respiratory failure who will have poor prognosis, in terms of 30-day readmission after discharge

Time frame: up to 27 months

Secondary Outcomes

Collection of Demographics (age, sex, marriage)

Time frame: up to 27 months

Number of participants with in-hospital death

Time frame: up to 27 months

Number of participants with 1-year death after discharge

Time frame: up to 27 months

Number of participants with 30-day readmission after discharge

Time frame: up to 27 months