Effect of Tadalafil on Erectile Dysfunction Treatment and QOL Improvement Effect (by SF-12) in Andropause Patients With Erectile Dysfunction

Inclusion Criteria: 1. Above 35 years men 2. Approving ADAM questionnaire and andropause patients with symptoms under contents ; easily fatigue, decreased sexual desire, general weakness, decreasing memory ect. 3. Patient with Erectile Dysfunction above 6 months 4. International Index of Erectile Function(IIEF-5) score under 21 5. Voluntarily one want to treatment with Tadalafil 5 mg daily 6. Voluntarily one agree this study and write informed consent Exclusion Criteria: 1. Persons who have taken PDE-5 inhibitor within last one month for Erectile Dysfunction 2. Persons who taken testosterone treatment within last one month 3. Persons who be history of Myocardiac infarction 4. The history of taken organic nitrate drug 5. The history of cardiovascular disease * In myocardial infarction within the last 90 days was now * Unstable angina or angina pectoris during intercourse that occurred * New York Heart Association Class 2 during the last six months or more sever cardiac failure * Uncontrolled arrythmia, hypotension(\<90/50mmHg), or uncontrolled blood pressure(\>170/100mmHg) * Persons who have a stroke within the last six months 6. Persons who have degrative retinal disease including Pigmentary retinites 7. Formerly persons who have one eye blindness by Artery anterior ischemic optic neuropathy with or without taking PDE5 inhibitor. 8. Persons who use inhibitor or agonist drug f Hepatic cytochrome P4503A4 9. Persons who use alpha antagonist add antihypertensive drug 10. Moderate liver or kidney failure 11. Major psychiatric or personality disorder 12. Persons have phobia trial drug 13. Persons have invasive treatment of prostate gland 14. Congenital anomaly of penis 15. Galactose, Lactose, Glucose intolerance patient 16. Research coordinators who are deemed unfit