The trial is to test the resolution of pain, swelling and other signs of periapical infection and the antimicrobial efficacy when using the neem leaf extract compared to chlorhexidine as root canal irrigant in Pulpectomy treatment for children.
To compare the effectiveness of neem leaf extract with that of Chlorhexidine gluconate when used as an intracanal irrigant in primary molar teeth indicated for pulpectomy treatment. P: children with primary necrotic molars indicated for pulpectomy I: Neem leaf extract (alcoholic solution). C: 2% chlorhexidine gluconate. O: Pain and swelling resolution. T:Over 12 months. S: Randomised controlled trial.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
40
A natural irrigant solution act as anti-inflammatory and anti bacterial
2%chlorhexidine gluconate , anti bacterial root canal irrigant solution
Pediatric dentistry and Public health department-Cairo University
Cairo, Egypt
Pain
Patient reported pain and pain on percussion , binary
Time frame: 1 year
Swelling
Visual examination ,binary
Time frame: 1 year
Mobility
Mobility test ,binary
Time frame: 1 year
Bacterial load
Bacteria on culture plates measuring unit CFU/ml
Time frame: 48 hours
Periapical pathosis
Periapical radiograph , binary
Time frame: 1 year
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