This study aims to investigate the changes induced by HABIT-ILE in impairments, activity and participation of children with unilateral CP, as well as neuroplastic changes induced by the treatment. Visuospatial deficits will be investigated and the effect of prismatic adaptation will be measured.
This study aims to investigate the changes induced by HABIT-ILE at the 3 levels of the international classification of functioning and health (ICF) in children with unilateral CP, as well as neuroplastic changes induced by the treatment. Visuospatial deficits will be investigated and the effect of prismatic adaptation will be measured.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
35
Bimanual and locomotor intensive intervention for 90h including 8 hours of prismatic adaptation
Bimanual and locomotor intensive intervention for 90h including 8 hours of prismatic adaptation wearing sham goggles.
Bleyenheuft Yannick
Brussels, Belgium
changes in star cancellation
number of little stars omitted in a frame including many stars of different size
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
change in "Ogden Figure" test
number of elements omitted when reproducing a drawing
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
changes in line bissection
deviation from midline during line section
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
visuo-spatial pointing
pointing in a blind box in the direction of a visual cue, measuring the deviation from midline
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
proprioceptive pointing
pointing without any visual feedback in the direction of body midline and measuring deviation
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
Jebsen-Taylor test of hand function
Manual dexterity measured with objects of everyday life, measure=time to manipulate objects
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
functional magnetic resonance imaging (fMRI)
cortical activation (changes in voxels activation)
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
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Box and blocks
number of blocks manipulated in one minute
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
Assisting Hand Assessment
help provided by the paretic hand to the non-paretic one in bimanual coordination
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
"ABILHAND-Kids" questionnaire
parents-reported questionnaire measuring manual ability
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
"ACTIVLIM-CP" questionnaire
parents-reported questionnaire measuring global activity performance
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
Canadian Occupationnal Performance Measure
setting therapeutic goals with parents and measuring both performance and satisfaction (%)
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
diffusion tensor imaging (DDTI)
measuring changes in white matter tracts (fractional anisotropy, number of voxels)
Time frame: at baseline and after 90 hours/two weeks of intensive bimanual intervention