The purpose of this study is to compare the analgesic profile of modified pectoral nerves block and serratus plane block in patients undergoing mastectomy.
This study includes three groups. The first group will receive ultrasound-guided modified pectoral nerves block prior to induction of general anesthesia. The second one will receive ultrasound-guided serratus plane block prior to induction of general anesthesia. The third one will not receive any block preoperatively.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
90
National Cancer Institute
Cairo, Misr Al Qadimah, Egypt
Fentanyl consumption
Time frame: Intraoperative
Total morphine consumption
Time frame: The first 24 hours postoperative
Visual analogue scale score at rest and during shoulder movement
Time frame: The first 24 hours postoperative
Mean arterial blood pressure
Hemodynamics
Time frame: Preincision, 1 minute postincision, 1 hour postincision, 4, 8, 12, 24 hours postoperative
Heart rate
Hemodynamics
Time frame: Preincision, 1 minute postincision, 1 hour postincision, 4, 8, 12, 24 hours postoperative
Time to first requirement of rescue analgesia
Time frame: The first 24 hours postoperative
Sedation score
as a side effect of morphine
Time frame: Immediate postoperative, 1, 4, 8, 12, 24 hours postoperative
Respiratory rate
respiratory depression defined as respiratory rate \<12 breaths per minute
Time frame: Immediate postoperative, 1, 4, 8, 12, 24 hours postoperative
Nausea and vomiting
as a side effect of morphine
Time frame: The first 24 hours postoperative
Patient satisfaction with postoperative analgesia
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using numerical rating scale from 0 to 10
Time frame: One week after surgery