Determine if antibiotic prophylaxis with intravenous cephalosporin and aminoglycoside in patients with Type II and II open fractures is safe and effective.
1. Determine the safety and efficacy of antibiotic prophylaxis in type II and II open fractures when using IV Cephalosporin and aminoglycoside. 2. Identify the incidence of acute kidney injury. 3. Identify the type and number of associated infections 4. Identify the antibiotic resistance profile noted 5. Identify any secondary infections at sites other than the fracture site
Study Type
OBSERVATIONAL
Enrollment
50
Triple O Research Institute PA
West Palm Beach, Florida, United States
Rate of fracture site infections
number of infections
Time frame: 30 days
Incidence of acute renal injury
number of patients with worsening renal function from baseline
Time frame: 30 days
type of bacteria infection
name of bacteria infection
Time frame: 30 days
resistance trend in patients with infections
describe the number of MDRO infections
Time frame: 30 days
number of secondary infections at site other than fracture sites
describe the number infections at secondary sites
Time frame: 30 days
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