Anemia and sideropenia are a common effect of untreated celiac disease. In a portion of patients a certain degree of hypoferritinemia persist after the diagnosis, despite a good compliance and clinical response to gluten-free diet. These patients are usually premenopausal women in whom the cyclic menstrual bleeding and the oral iron intake are not balanced. The aim of the study is to compare the efficacy of a pharmacological therapy, frequently not tolerated, and a dietary approach through a iron-rich diet in this subset of patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
35
Daily supplementation with iron sulfate 105 mg 1 pill/day
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
Milan, Milan, Italy
RECRUITINGFerritin levels (ng/mL) increase > 95% compared to basal levels
Time frame: 12 weeks
Hemoglobin levels (g/dL), compared to basal levels
Time frame: 12 weeks
Iron levels (mcd/dl), compared to basal levels
Time frame: 12 weeks
Transferrin saturation (%, ratio of serum iron and total iron-binding capacity), compared to basal levels
Time frame: 12 weeks
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