The purpose of this study is to determinate the AMH levels before and after antiviral therapy with Ombitasvir-Paritaprevir-Ritonavir and Dasabuvir in comparison with age-matched HCV-positive women not undergoing antiviral treatment.
The study is interventional, controlled randomized (block 2:1 case: controls) in open label.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
75
Gastroenterology Unit
Modena, Modena, Italy
The modification of AMH levels
The primary outcome is to evaluate the modification of AMH levels before and after successful antiviral therapy in comparison with age-matched HCV-positive women not undergoing antiviral treatment is the primary endpoint
Time frame: 48 weeks post treatment
Modification of AMH levels
Modification of AMH levels before and after successful antiviral therapy
Time frame: 144 weeks
Modification of the Estradiol (E2) levels
Modification of the Estradiol (E2) levels before and after successful antiviral therapy in comparison with age-matched HCV-positive women not undergoing antiviral treatment is the primary endpoint
Time frame: 144 weeks
Percentage of participants experiencing miscarriage
Percentage of participants experiencing miscarriage during 3 years observation post-therapy.
Time frame: 144 weeks
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