The study is a prospective interventional study with three main aims: 1. Describe the frequency and severity of withdrawal syndrome in a population of paediatric intensive care patients. 2. Test whether implementation of an algorithm for tapering of analgosedation changes the frequency and severity of withdrawal symptoms in the same population. 3. Investigate how the health care providers experience having to adhere to such an algorithm.
Patients \< 18 years of age treated in an intensive care unit for 5 days or more with infusion of opioids and/or benzodiazepines, are eligible for inclusion. Patients are included at the time tapering of these drugs is initiated. Part one of the study is observational. Drugs administered, complications, Comfort score and WAT-1 (Withdrawal Assessment Tool-1) score is recorded. Before part two of the study, an algorithm for tapering of analgosedation is implemented, and the data set is obtained as in part one. For part three of the study, focus group interviews will be used.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
80
Algorithm for tapering og analgosedation
Oslo University Hospital, Rikshospitalet
Oslo, Norway
Change in mean peak WAT-1 score
Time frame: Through study completion, up to 21 days
Time used tapering analgosedation
Time frame: Through study completion, up to 21 days
Ventilator days
Time frame: Through study completion, up to 21 days
ICU days
Time frame: Through study completion, up to 21 days
Drug doses used
Time frame: Through study completion, up to 21 days
Adverse events
Time frame: Through study completion, up to 21 days
Comfort score
Time frame: Through study completion, up to 21 days
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