Acceptance and Commitment Therapy in SSRI-Resistant Obsessive Compulsive Disorder

Inclusion Criteria: 1. age between 18 and 65; 2. no less than 9 years in education; 3. a DSM-IV diagnosis of OCD 4. moderately symptomatic (Yale-Brown Obsessive Compulsive Scale score≥16) 5. received at least two kinds of SSRIs at optimal dose for more than 12 weeks An optimal dose is described as following: clomipramine hydrochloride, at least 225 mg/d;fluoxetine, at least 60 mg/d; paroxetine hydrochloride, at least 60 mg/d; sertraline hydrochloride, at least 200 mg/d; fluvoxamine, at least 250 mg/d; citalopram hydrobromide,at least 60 mg/d; and escitalopram oxalate, at least 40 mg/d.Patients who are unable to tolerate the supposed optimal doses were also eligible if at their maximally tolerated dose. Exclusion Criteria: 1. with comorbid Axis I psychiatric disorders 2. drug abuse in the last 3 months 3. HAMD\>25 4. too severe to receive ACT or evaluation 5. at high risk of suicide 6. pregnant or prepare for pregnancy 7. with somatic disorder 8. received aripiprazole(≥10mg for 8weeks) or ACT(8 times within 2 months) before 9. treated with no more than one kind of SSRI before