Iodinated contrast media are now frequently used in diagnostic imaging exams, including pediatrics. In adults, the acute renal failure (ARF) associated with contrast agents (CA-AKI) occur in 3-33% of exposed patients, especially as the patient is fragile, has comorbidities or pre-existing renal aggression . In children, the prevalence of this little known disease is probably underestimated. The investigators intend to conduct a prospective epidemiological study, to estimate the impact of the acute renale failure to iodinated contrast agents in pediatrics.
Patients will be included those of pediatric emergencies, Hospitalization Unit of Short Duration pediatric, pediatric intensive care and pediatric resuscitation. The acute renale failure will be estimated on the basis of criteria KDIGO (score of kidney disease) group in 2012 to 48 hours a computed tomography (CT) scan with injection of contrast media, based on a change in creatinine clearance of the estimated according to the formula Schwartz revised in 2009 and / or diuresis. Patient characteristics will be identified in order to establish risk factors.
Study Type
OBSERVATIONAL
Enrollment
4
Before the CT scan, the investigators with iodinated contrast agents, the following data will be collected in the medical record: creatinine prior to injection, comorbidities and child characteristics, associated treatments and risk factors of acute renal failure, as well as the injection pattern. After the CT scan the investigators will collect the characteristics of the injection type, osmolarity and volume of contrast used and the appearance of a possible allergic reaction. Then 24 and 48 hours and day 7 will collect serum creatinine, urine output and vital replacement therapies may be necessary.
CHU de Lyon
Lyon, France
Chu Saint-Etienne
Saint-Etienne, France
Creatinine
data gathered in the medical file
Time frame: change from baseline creatinine at 7 days
Diuresis
data gathered in the medical file
Time frame: change from baseline diuresis at 7 days
Readmission
Number of patients with no or having an adverse event during the readmission.
Time frame: at 7 days
Hospitalization in intensive care
Number of patients with no or having an adverse event during the hospitalization in intensive care.
Time frame: at 7 days
Renal replacement
Number of patients with no or having an adverse event during the renal replacement.
Time frame: at 7 days
Death
Number of dead
Time frame: at 7 days
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