Polyethylene Glycol Versus Low Volume Solutions Prior to Colonoscopy

Tomas Bata Hospital, Czech Republic1,044 enrolled

Overview

Study evaluates the efficacy and tolerability of low volume preparations compared with conventional 4L polyethylene glycol prior to colonoscopy

To compare the efficacy and tolerance of standard polyethylene glycol to low volume sodium picosulphate/magnesium citrate and polyethylene glycol/ascorbic acid in a single or split dose regimen for colonoscopy bowel preparation in a head-to-head design.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

1,044

Conditions

Colonoscopy

Interventions

Polyethylene GlycolsDRUG

Natrium picosulfate / Magnesium citrateDRUG

Polyethylene glycol / Ascorbic acidDRUG

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects referred to diagnostic or therapeutic colonoscopy Exclusion Criteria: * ileus * known or suspected bowel obstruction * active bowel inflammation * pregnancy * any presence of serious medical conditions * history of prior colonic or rectal surgery * inability to obtain valid data from subject

Locations (1)

Faculty Hospital Kralovske Vinohrady

Prague, Czechia

Outcomes

Primary Outcomes

Quality of Bowel Preparation Using the Aronchick Scale ( Score 1+2)

Bowel preparation score 1+2 expressed on Aronchick scale (1 the best, 5 the worst)

Time frame: One day

Secondary Outcomes

Tolerance of Bowel Preparation Assessed by 5 Point VAS ( Score 1+2)

Tolerance of Bowel Preparation Assessed by VAS score 1+2 ( 1-excellent, 5-very poor)

Time frame: One day

Data from ClinicalTrials.gov

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