Results have indicated that some dietary fibers increase fecal fat excretion and particularly viscous fibers suppress appetite sensation and reduce energy intake. Both these effects may contribute to body weight management. Aim: The aim of the study is to investigate the potential of 3-weeks daily intake of potato pulp (FiberBind), rhamnogalacturonan I isolated potato fiber (RG-I) vs. a low-fiber control (placebo) on satiety and fecal fat excretion in healthy adults. Furthermore, a number of secondary endpoints are investigated.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
18
Potato pulp consisting of 68% fiber (5.5 soluble, 76.7% insoluble and 17.8% resistant starch), 9.7% water, 0.3% fat, 7.2% protein and 14% carbohydrates (starch).
Soluble fiber extracted from potato pulp consisting of 95% fiber and 5% water.
Low-fiber control
University of Copenhagen, Department of Nutrition, Exercise and Sports
Copenhagen, Denmark
Fecal fat excretion
Time frame: Based on total feces collection the last 3 days of the 21-day intervention periods
Subjective appetite sensations
Assessed by visual analogue scales (VAS)
Time frame: Assessed on 3-hour meal test on last day of the 21-day intervention periods
Ad libitum energy intake
Time frame: Assessed 3 hours after intake of the test meal on last day of the 21-day intervention periods
Fecal energy excretion
Time frame: Measured based on total feces collection the last 3 days of the 21-day intervention periods
Blood lipids (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides)
Time frame: Measured before and after the 21-day intervention periods
Insulin and glucose
Time frame: Measured before and after the 21-day intervention periods, and every 30 minutes during the 3-hour meal test on last day of the 21-week intervention periods
Gut permeability marker
Time frame: Measured before and after the 21-day intervention periods
Gastric emptying rate (w. paracetamol)
Time frame: Measured every 30 minutes during the 3-hour meal test on last day of the 21-day intervention periods
Gastrointestinal symptoms (questionnaire)
Time frame: on day 1, 7, 14 and 22 of the 21-day intervention periods
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Body weight
Time frame: up to 21-day intervention periods
Blood pressure
Time frame: up to 21-day intervention periods
Breath hydrogen
Time frame: up to 21-day intervention periods
Gut microbiota
Time frame: Measured in a fresh feces sample from day 19-21 of the intervention periods