This study aims to evaluate the efficacy of intense pulsed light in treating dry eye caused by meibomian gland dysfunction and make a comparison between the traditional treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
20
Intense pulse light (IPL) has been used in dermatology practices for several years as a treatment for rosacea and acne.IPL uses Xenon flashlamp to emit wavelengths of light from 400 to 1200nm. When placed on the light, a filter restricts the wavelength to the visible light range of \*500nm.In 2007-2008, an IPL treatment technology-the Diamond Q4 by DermaMed Solutions-was specifically configured to our specifications with the goal of stimulating secretion of normal meibum via skin treatment effects on the meibomian glands. It was discovered that dry eye patients are better positioned for gland expression, as IPL seems to liquefy the abnormal viscous meibum and dilate the glands.
Ocular Surface Disease Index (OSDI)
normal value：\<13 abnormal value：≥ 13
Time frame: through study completion,an average of 6 months
The concentrations of inflammatory cytokines such as IL-1、IL-6 and IL-8
Time frame: through study completion,an average of 6 months
breakup time of tear film （BUT）
normal value：\>10s abnormal value：≤ 10s
Time frame: through study completion,an average of 6 months
Corneal Fluorescein Stain(CFS)
Time frame: through study completion,an average of 6 months
Eyelid ester discharge ability score
Time frame: through study completion,an average of 6 months
Eyelid ester trait ratings
Time frame: through study completion,an average of 6 months
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