The aim of this study is to investigate discriminant metabolites in urine from patients with rheumatoid arthritis (RA) from healthy individuals. Then we determine if the patient's metabolic fingerprint could predict the development or flare-up of RA.
Compare metabolites between RA patients and healthy individuals. 1. Collection urine sample 2. Assessing urine metabolites by 1H NMR spectroscopy 3. Analyzing the relationships between metabolites and clinical variables
Study Type
OBSERVATIONAL
Enrollment
200
Metabolic fingerprint of rheumatoid arthritis
Metabolomic analyses of urine from patients with rheumatoid arthritis, healthy controls and other autoimmune disease
Time frame: 1 years
Correlations between specific metabolites and disease activity/severity of RA
Identified metabolites and their clinical significances
Time frame: 1 year
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