the Effect of Dexmedetomidine in Coracoid Approach Brachial Plexus Block

The First Hospital of Qinhuangdao60 enrolled

Overview

Dexmedetomidine is an α-2 adrenoreceptor agonist and has been extensively used through intravenous infusion，in order to improved the quality of block in regional anesthesia. In this prospective, randomized study, the authors focus on the effect of dexmedetomidine mixed with ropivacaine in coracoid approach brachial plexus block.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Injury of Upper Limb

Interventions

ropivacaineDRUG

40 ml 0.375% ropivacaine was injected after Locating brachial plexus.

ropivacaine mixed with dexmedetomidineDRUG

40 ml 0.375% ropivacaine mixed with dexmedetomidine was injected after Locating brachial plexus.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. American Society of Anesthesiologists (ASA) physical status I or II; 2. Aged 18-60 years; 3. The elbow, forearm, wrist or hand surgery Exclusion Criteria: 1. History of allergy to local anesthetics; 2. Coagulation dysfunction, neuromuscular disease or local infection; 3. The operation time is longer than the local anesthetics effective time.

Outcomes

Primary Outcomes

duration time

effective analgesia time

Time frame: once per hour after surgery until 24 hours after surgery

Secondary Outcomes

onset time

Time frame: 5,10,15,20,25,30 min after injection

Visual analogue scale

Time frame: 2,6,12,24hour after injection

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.