The Safety and Efficacy Study of HU-014 Versus Botox® in Subject With Moderate to Severe Glabellar Lines

Inclusion Criteria: * Facial Wrinkle Scale (FWS) score \> 2 when Subject knits brow extremely Exclusion Criteria: * Volunteer who has history of any diseases following. (myasthenia gravis, Eaton-Lambert syndrome, amyotrophic lateral sclerosis etc.) * From screening, Subject who get a plastic Surgery including fascioplasty, Prosthesis implantation within 6 Weeks * Subject who has skin disorder including infection and scar on injection site * Subject who takes a medication including skeletal muscle relaxants, Aminoglycoside, lincomycin, anticholinergic drug, benzodiazepine, benzamide etc. * Subject who takes a medication including anticoagulant, antithrombotic drug except low dose aspirin (below 325 mg/day) * Any condition that, in the view of the investigator, would interfere with study participation