Bronchopleural fistula (BF), an abnormal passage or communication between a bronchus and another part of the body, may develop when there are penetrating wounds of the thorax and after lung surgery. Without effective therapy, treatment of BF is a challenge, with a high rate of mortality and teratogenicity. The investigators will conduct endoscopic injection of umbilical cord mesenchymal stem cells to fistula, observe the recovery of bronchopleural fistula and systemic reactions, to investigate the application of umbilical cord mesenchymal stem cells in the treatment of bronchopleural fistula.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
10
UCMSC: umbilical cord mesenchymal stem cells 3-5\*10\^7/5 ml
The Second Affiliated Hospital of Fujian Medical University
Quanzhou, Fujian, China
RECRUITINGclosure of the fistula
median time for fistula closure
Time frame: 24 weeks
complication
fever, coughing up blood, infection...
Time frame: 1 year
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