The main goal of this study is to determine if supplemental oxygen given only when the patient is inspiring (demand delivery) is more effective than constant-flow oxygen given during all phases of the breath regardless if the patient is breathing it in. A previous study in volunteers (NCT02886312) showed that the oxygen saturation in the blood and the concentration of oxygen breathed out from the lungs (end-tidal oxygen) was higher when given in demand (inhalation only) mode. A secondary goal is to determine in patients, whether turning oxygen delivery off during expiration improves the accuracy of end-tidal CO2 (Carbon Dioxide) monitoring. This was found to be the case in the previous volunteer study. The investigators want to determine if these improvements are also observable in relatively healthy patients undergoing procedural sedation and analgesia. The efficacy of the demand mode will be determined by measuring the resulting difference in oxygen saturation and end-tidal oxygen levels. The investigators will alternate between traditional oxygen delivery (continuous flow) and demand delivery (flow only during inhalation) for two minutes in each mode after which oxygen saturation and end-tidal oxygen will be measured. End-tidal CO2 measurement will be compared with those during the brief time when O2 flow is stopped.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
100
Supplemental oxygen flow is controlled such that it is on only during inhalation.
Supplemental oxygen flow is constantly on, irrespective of whether the patient is inhaling or exhaling.
Supplemental oxygen flow is stopped completely for a brief period to allow undisturbed end-tidal oxygen and CO2 measurements
University of Utah
Salt Lake City, Utah, United States
End-tidal Oxygen
Did the novel system increase end-tidal oxygen?
Time frame: measured every 140 seconds minutes throughout the surgical procedure
Oxygen Saturation
Did the novel system increase oxygen saturation?
Time frame: measured continuously with every heart beat (i.e., approx. every 500-2000msec) throughout the surgical procedure
End-tidal Carbon Dioxide
Was end-tidal carbon dioxide measured more accurately using the novel system?
Time frame: measured every 140 seconds minutes throughout the surgical procedure
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